All journal publications

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2011
Knibbe, C.A., Krekels, E.H., Danhof, M. , Advances in paediatric pharmacokinetics, Expert Opin Drug Metab Toxicol, vol. 7, no. 1, pp. 1-8. DOI
Syvänen, S., Luurtsema, G., Molthoff, C.F., Windhorst, A.D., Huisman, M.C., Lammertsma, A.A., Voskuyl, R.A., de Lange, E.C. , (R)-[11C]Verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus, BMC Med Imaging, vol. 11, pp. 1. DOI
2010
van Steeg, T.J., Krekels, E.H., Freijer, J., Danhof, M., de Lange, E.C. , Effect of altered AGP plasma binding on heart rate changes by S(-)-propranolol in rats using mechanism-based estimations of in vivo receptor affinity (K(B,vivo)), J Pharm Sci, vol. 99, no. 5, pp. 2511-20. DOI
De Cock, R.F., Piana, C., Krekels, E.H., Danhof, M., Allegaert, K., Knibbe, C.A. , The role of population PK-PD modelling in paediatric clinical research, Eur J Clin Pharmacol. DOI
Cella, M., de Gorter Vries, F., Burger, D., Danhof, M., Della Pasqua, O. , A model-based approach to dose selection in early pediatric development, Clin Pharmacol Ther, vol. 87, no. 3, pp. 294-302. DOI
Krekels, E.H., DeJongh, J., van Lingen, R.A., van der Marel, C.D., Choonara, I, Lynn, A.M., Danhof, M., Tibboel, D., Knibbe, C.A. , Predictive performance of a recently developed population pharmacokinetic model for morphine and its metabolites in new datasets of (preterm) neonates, infants and children, Clin Pharmacokinet, vol. 50, no. 1, pp. 51-63. DOI
Krekels, E.H., van Hasselt, J.G., Tibboel, D., Danhof, M., Knibbe, C.A. , Systematic Evaluation of the Descriptive and Predictive Performance of Paediatric Morphine Population Models, Pharm Res. DOI
Stevens, J., van den Berg, D.J., de Ridder, S., Niederlander, H.A., van der Graaf, P.H., Danhof, M., de Lange, E.C. , Online solid phase extraction with liquid chromatography-tandem mass spectrometry to analyze remoxipride in small plasma-, brain homogenate-, and brain microdialysate samples, J Chromatogr B Analyt Technol Biomed Life Sci, vol. 878, no. 13-14, pp. 969-75. DOI
Peeters, M.Y., Allegaert, K., van Blusse Oud-Alblas, H.J., Cella, M., Tibboel, D., Danhof, M., Knibbe, C.A. , Prediction of propofol clearance in children from an allometric model developed in rats, children and adults versus a 0.75 fixed-exponent allometric model, Clin Pharmacokinet, vol. 49, no. 4, pp. 269-75. DOI
2009
Santen, G., van Zwet, E., Danhof, M., Della Pasqua, O. , From trial and error to trial simulation. Part 1: the importance of model-based drug development for antidepressant drugs, Clin Pharmacol Ther, vol. 86, no. 3, pp. 248-54. DOI
Santen, G., Horrigan, J., Danhof, M., Della Pasqua, O. , From trial and error to trial simulation. Part 2: an appraisal of current beliefs in the design and analysis of clinical trials for antidepressant drugs, Clin Pharmacol Ther, vol. 86, no. 3, pp. 255-62. DOI
Clinckers, R., Smolders, I, Vermoesen, K., Michotte, Y., Danhof, M., Voskuyl, R., Della Pasqua, O. , Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations, Expert Opin Drug Metab Toxicol, vol. 5, no. 10, pp. 1267-77. DOI
Stevens, J., Suidgeest, E., van der Graaf, P.H., Danhof, M., de Lange, E.C. , A New Minimal-Stress Freely-Moving Rat Model for Preclinical Studies on Intranasal Administration of CNS Drugs, Pharm Res. DOI
Huntjens, D.R., Spalding, D.J., Danhof, M., Della Pasqua, O.E. , Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors, Eur J Pain, vol. 13, no. 5, pp. 448-57. DOI
Maas, H., Danhof, M., Della Pasqua, O. , Analysis of the relationship between age and treatment response in migraine, Cephalalgia. DOI
Rip, J., Schenk, G.J., de Boer, A.G. , Differential receptor-mediated drug targeting to the diseased brain, Expert Opin Drug Deliv, vol. 6, no. 3, pp. 227-37. DOI
Ince, I, de Wildt, S.N., Tibboel, D., Danhof, M., Knibbe, C.A. , Tailor-made drug treatment for children: creation of an infrastructure for data-sharing and population PK-PD modeling, Drug Discov Today, vol. 14, no. 5-6, pp. 316-20. DOI
Diepstraten, J., van Kralingen, S., Snijder, R.J., Hackeng, C.M., van Ramshorst, B., Knibbe, C.A. , Treatment of Pulmonary Embolism in an Extremely Obese Patient, Obes Surg. DOI
Gaasbeek, E.J., van der Wal, F.J., van Putten, J.P., de Boer, P., van der Graaf-van Bloois, L., de Boer, A.G., Vermaning, B.J., Wagenaar, J.A. , Functional characterization of excision repair and RecA-dependent recombinational DNA repair in Campylobacter jejuni, J Bacteriol, vol. 191, no. 12, pp. 3785-93. DOI
Verpoorte, R., Crommelin, D., Danhof, M., Gilissen, L.J., Schuitmaker, H., van der Greef, J., Witkamp, R.F. , Commentary: "A systems view on the future of medicine: inspiration from Chinese medicine?", J Ethnopharmacol, vol. 121, no. 3, pp. 479-81. DOI
Liefaard, L.C., Ploeger, B.A., Molthoff, C.F., de Jong, H.W., Dijkstra, J., van der Weerd, L., Lammertsma, A.A., Danhof, M., Voskuyl, R.A. , Changes in GABAA receptor properties in amygdala kindled animals: in vivo studies using [11C]flumazenil and positron emission tomography, Epilepsia, vol. 50, no. 1, pp. 88-98. DOI
Ploeger, B.A., Smeets, J., Strougo, A., Drenth, H.J., Ruigt, G., Houwing, N., Danhof, M. , Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex, Anesthesiology, vol. 110, no. 1, pp. 95-105. DOI
Ploeger, B.A., Smeets, J., Strougo, A., Drenth, H.J., Ruigt, G., Houwing, N., Danhof, M. , Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex, Anesthesiology, vol. 110, no. 1, pp. 95-105. DOI
Bartelink, I.H., Bredius, R.G., Belitser, S.V., Suttorp, M.M., Bierings, M., Knibbe, C.A., Egeler, M., Lankester, A.C., Egberts, A.C., Zwaveling, J., Boelens, J.J. , Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematologic stem cell transplantation, Biol Blood Marrow Transplant, vol. 15, no. 2, pp. 231-41. DOI
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